Cthrc1 gene
WebJul 29, 2013 · Collagen triple helix repeat containing-1 (CTHRC1) is a secreted glycoprotein that activates the planar cell polarity pathway of Wnt signaling. Using microarray analysis, we found that the CTHRC1 gene is overexpressed in hepatocellular carcinoma (HCC). The level of CTHRC1 mRNA was measured in 201 surgically resected … WebOct 8, 2012 · Generation of Cthrc1 null mice. (A) Cthrc1 gene targeting schematic showing replacement of exons 2-4 with a PGK-neo cassette. (B) Embryonic stem cell targeting with Southern blot analysis of ...
Cthrc1 gene
Did you know?
WebDec 1, 2001 · Disease susceptibility is associated with variants affecting the gene represented in this entry Description A condition characterized by a metaplastic … WebMar 21, 2024 · CTHRC1 serves as a pro-metastatic gene that contributes to NSCLC invasion and metastasis, which are mediated by upregulated MMP7 and MMP9 …
WebOct 6, 2024 · According to the previous reports, the collagen triple helix repeat containing 1 (CTHRC1) causes tumorigenesis by modulating the tumor microenvironment, however, the evidence is limited to a few human cancer subtypes. ... (GEO) based datasets. During the analysis, we simply queue the CTHRC1 gene in these databases to acquire the KM … WebMethods: DEGs were screened from four GEO (Gene Expression Omnibus) gene expression profiles. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed. ... Collagen Type X Alpha 1 Chain (COL10A1), Collagen Triple Helix Repeat Containing 1 (CTHRC1), and Fibroblast Activation Protein (FAP) …
WebJul 19, 2024 · Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein. … WebSep 9, 2008 · Methodology/Principal Findings. We identified collagen triple helix repeat containing-1 (Cthrc1) as a downstream target of bone morphogenetic protein-2 (BMP2) in osteochondroprogenitor-like cells by PCR-based suppression subtractive hybridization followed by differential hybridization, and found that Cthrc1 was expressed in bone …
WebDec 22, 2024 · The X-axis represent ligand and receptor pairs, with the first gene expressed on F13-Act-CTHRC1 cells and second gene expressed on the interacting cell types denoted in the Y-axis. Red: upregulated gene in tumor bulk RNA-seq. Blue: downregulated in tumor bulk (none present).
WebAug 30, 2024 · Gene ID: 68588, updated on 30-Aug-2024. Summary Other designations. collagen triple helix repeat-containing protein 1. GeneRIFs: Gene References Into Functions. GPR180 is a component of TGFbeta signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor … the ultimate gift card studentWebMar 1, 2024 · Expression of CTHRC1 in Patients With COAD Under Different Physiological or Pathological States. UALCAN analysis showed that the expression level of CTHRC1 was significantly higher in the patients with primary COAD than that in normal tissues ().Notably, this abnormally high expression pattern is generally applicable to patients with different … the ultimate gift phimmoiWebFeb 22, 2007 · We identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene expressed in the adventitia and neointima on arterial injury and found that it functionally increases cell migration while reducing collagen deposition. To address the in vivo role of Cthrc1, we generated transgenic mouse lines that constitutively overexpress … sfnywebspw02/user/logonWebBackground: We discovered the gene Collagen Triple Helix Repeat Containing 1 (Cthrc1) and reported its developmental expression and induction in adventitial cells of injured … sfo 10-day weatherWebAug 30, 2024 · The occurence frequency of CTHRC1 gene is higher in multiple Wnt signaling pathway associated with enrichment classes. Furthemore, CTHRC1 gene is positively correlated with ANOS1. This implies that CTHRC1 probably plays an important role in the gene function/process of ANOS1. Many studies have investigated the role of … the ultimate gift jim stovall ebayWebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the … sfn travel award 2017WebJun 15, 2024 · Gene expression of Cthrc1 was significantly increased from day 3, peaked at day 5, and fell back at day10 after injury (Fig. 1a). To verify this result, we examined the … sfn single frequency network